Synthetic oligonucleotides: AFM characterisation and electroanalytical studies
نویسندگان
چکیده
منابع مشابه
AFM and electroanalytical studies of synthetic oligonucleotide hybridization.
The first and most important step in the development and manufacture of a sensitive DNA-biosensor for hybridization detection is the immobilization procedure of the nucleic acid probe on the transducer surface, maintaining its mobility and conformational flexibility. MAC Mode AFM images were used to demonstrate that oligonucleotide (ODN) molecules adsorb spontaneously at the electrode surface. ...
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ژورنال
عنوان ژورنال: Bioelectrochemistry
سال: 2005
ISSN: 1567-5394
DOI: 10.1016/j.bioelechem.2004.06.008